Does Mounjaro Make You Tired? What You Need to Know
When you start a new medicine like Mounjaro, your body needs time to adjust. At first, you might feel strange. Tiredness may be part of that. But this usually gets better as your body gets used to the medication.

Overview
Treatment with medicines generally leaves you with certain side effects, especially medications for weight loss. If you are aiming to shed some pounds with Mounjaro, no doubt it’s a good choice, as it is helpful to manage diabetes type 2. Several people are now using Mounjaro to lose weight. But some users have experienced that they feel tired after taking it. This has led many people to ask, does Mounjaro make you tired?
In this article, we’ll look at what Mounjaro is, how it works, and if it can really make you feel weak or tired. We’ll also share simple tips to feel better if you’re dealing with tiredness while on Mounjaro.
What Is Mounjaro?
Mounjaro is a shot you take once a week. The main ingredient of this incredible drug is called tirzepatide. It was first designed to help individuals manage type 2 diabetes. But doctors also found it helps people lose weight. So now, many people who are overweight or have obesity are using it as well. It can also be your choice.
Let’s discuss how Mounjaro works. Mounjaro works by mimicking two hormones present in your body called GLP-1 and GIP. These hormones help your body
- To make more insulin,
- Lower blood sugar
- Make you feel full longer.
- Help you eat less and lose weight
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Can mounjaro make you tired?
Tiredness is not one of the main side effects listed for Mounjaro. However, some people do say they feel
more tired than usual when taking it. So, let’s try to understand why this might happen. Stay connected with us to explore the main reasons.
1. Tiredness from low calories
Mounjaro helps people lose weight by making them feel full. Because of this, some people eat much less food than before. If you’re eating too little, your body might not get the energy it needs. This can make you feel weak or tired.
Also, not eating enough can lead to low blood sugar. Low blood sugar can make you feel shaky, dizzy, or very sleepy.
2. Tiredness from stomach problems
Some people feel sick to their stomach after taking Mounjaro. You might feel:
- Nausea
- Vomiting
- Diarrhea
Note: If you have these problems often, your body can lose a lot of water. Dehydration can make you feel very tired and drained.
3. Your body is adjusting
When you start a new medicine like Mounjaro, your body needs time to adjust. At first, you might feel strange. Tiredness may be part of that. But this usually gets better as your body gets used to the medication.
4. Other health issues
Feeling tired all the time may not be from Mounjaro at all. It could be a sign of:
- Poor sleep
- Lack of iron
- Thyroid problems
- Anxiety or depression
Note: If you’re hesitant, it’s best to converse with your healthcare provider.
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How common is tiredness on Mounjaro?
Typically, in most medical studies, health experts don’t list tiredness as a main side effect of Mounjaro. On the other hand, the most common side effects people experienced are
- Nausea
- Vomiting
- Diarrhea
- Constipation
Note: Still, every person is different. Some may feel sleepy or low on energy, even if it’s not common. If you notice tiredness soon after starting Mounjaro, it’s a good idea to track your symptoms and talk with your provider.
How to feel less tired on mounjaro
If Mounjaro is making you feel tired, don’t worry. Here we are suggesting you to do feel better after experiencing tiredness.
1. Drink more water
Dehydration is one of the main causes of tiredness due to using Mounjaro. If you’re losing fluids because of vomiting or diarrhea, your body needs more water.
Try this
- Sip water slowly throughout the day.
- Drink water with slices of cucumber or lemon if plain water irritates your stomach.
- Avoid too much coffee or soda, as these can dehydrate you.
2. Eat small meals often
If Mounjaro makes you feel full quickly, try eating smaller meals more often. This can help keep your energy up.
- Add healthy snacks to your diet plan, like yogurt, nuts, and fruit.
- Avoid skipping meals, even if you’re not very hungry.
- Choose foods that give steady energy: whole grains, eggs, lean meats, and veggies.
3. Focus on protein
Protein gives you long-lasting energy. It also helps keep your muscles strong while you lose weight.
Good sources of protein include
- Eggs
- Chicken or turkey
- Tofu
- Beans and lentils
- Greek yogurt
- Try to consume a meal having some protein with every meal.
4. Get moving
Exercise can actually boost your energy. You do not need to run or go to the gym daily. Even a short walk can help wake up your body and mind.
Tips:
- Take a 10-minute walk in the morning.
- Stretch for a few minutes each hour.
- Try light yoga or swimming if you feel up to it.
Note: Before starting a new exercise routine, discuss it with your provider, especially if you’re new to physical training.
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5. Get enough sleep
Not getting enough sleep is a common reason people feel tired. Try to get 7-9 hours of sleep each night.
Here are some tips for better sleep:
- Sleep at the same time every night.
- Turn off screens (like phones or TVs) 30 minutes before bed.
- Keep your room cool, dark, and quiet.
When should you call your doctor?
While some tiredness is normal, you should talk to your doctor if:
- You feel tired all the time
- You can’t stay awake during the day
- You feel weak and dizzy often
- You’re not eating or drinking enough
- You’ve lost too much weight too fast
Note: These signs could mean your body is not handling Mounjaro well, or you might need a lower dose.
Can you stay on Mounjaro if it makes you tired?
Yes, in most cases, you can continue taking Mounjaro if you feel tired. But you should talk to your doctor. They might:
- Adjust your dose
- Check your blood sugar levels
- Help you plan better meals
- Look for other health reasons that could be causing your tiredness
The goal is to help you lose weight safely and feel good while doing it.
What do real people say?
Many people using Mounjaro have shared their experiences online. Here’s what some have said about tiredness. So keep reading and stay connected to take your final decision to use Mounjaro
“I felt tiredness in the first few weeks, but it went away after my body got used to the Mounjaro.”
“The nausea made me eat less, and I had low energy. Once I started eating better meals, I felt more awake.”
“I had to decrease my dosage due to feeling extremely tired. My provider helped me find the right balance.”
Everyone’s experience is different. You just need to listen to your body, and staying in touch with your provider can help you manage side effects more healthily.
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Final thoughts: Does Mounjaro make you tired?
Does Mounjaro make you tired? For some people, yes. But for most, this feeling is short-term and manageable. Tiredness might happen due to low calorie intake, poor sleep, stomach side effects, or other health issues.
The good news? You don’t have to live with low energy. With small changes in your diet, water intake, sleep, and activity levels, you can feel better and still enjoy the benefits of Mounjaro.
If you’re worried about feeling tired on Mounjaro, don’t be afraid to ask your doctor for help. They can make sure the medicine is working for you—and not making you feel worse.
Get support on your journey
Losing weight and managing your health is not easy, but you don’t have to do it alone. Whether you’re on Mounjaro or just starting your journey, having the right support makes a big difference.
Talk to your healthcare providers, join a support group, or use a health app to track your progress. Stay informed, take care of yourself, and keep your energy up—you’ve got this